CBD Oil vs. Water Soluble CBD Oil
CBD Oil and Water CBD
Cannabidiol (CBD) is one of the most important – though least studied – derivatives of Cannabis, which is developing a reputation as the cure of the moment. Nevertheless, science knows very little about what it does in the human body. Most people think of Marijuana when they mention Cannabis; but CBD is a Hemp derivative, a plant that belongs to the same cannabis family.
Hemp and marijuana are two different varieties of the plant Cannabis Sativa. On one hand, marijuana has high levels of THC, the main responsible for its psychoactive properties. On the other hand, Hemp has almost undetectable levels of THC, however, presents relatively high levels of CBD. Even so, CBD can placate the effects of the small amount of THC found in hemp.
Thanks to the combination of different varieties of Cannabis Sativa, and the development of genetics and cultivation techniques, it has been possible to produce hemp with an exceptionally high percentage in CBD, getting an oil rich in CBD and not psychoactive.
Benefits of CBD Oil
CBD is in the uncomfortable position of being a substance not recognized as medicinal, but which undoubtedly has therapeutic properties. Currently, there are 2,034 research results on cannabidiol in PubMed, the online information source of the National Library of Medicine and the U.S. National Institutes of Health.
Researchers have occasionally described CBD as being of even greater medical importance than THC. Its lack of psycho-activity is a great advantage, as people can use it safely and without fear of intoxication. Beyond this, it has many known beneficial properties. The following lines will mention some of the most studied benefits to date, both in laboratory research and in clinical trials:
Studies suggest that CBD has properties for reducing the severity and frequency of epileptic seizures in children resistant to drugs created for this purpose. The number of clinical trials conducted to explain the effectiveness of CBD is increasing to know the real potential of this compound.
- Neuroprotective and anti-inflammatory effects
Researchers have studied these properties within models of diseases such as Alzheimer’s, Multiple Sclerosis, Parkinson’s disease, glutamate toxicity and neurodegeneration caused by alcohol. In double-blind clinical trials in patients with Parkinson’s disease, they report improvement in the parameters known as the Quality-of-life scale.
- Anti-anxiolytic effect
In laboratory protocols designed to simulate post-traumatic stress disorder, scientists found that CBD improves the “consolidation of extinction,” in other words, forgetting traumatic experiences/memories.
- Cannabidiol and inhibition of cancer cell proliferation
Perhaps most excitingly CBD have shown is to have an inhibitory effect on the cancer cells proliferation. The effect of CBD on cannabinoid receptors CB2 and TRPV1 plays a role here, through the induction of oxidative stress. Systemic biological functions produce reactive oxygen species (ROS) such as peroxides, oxygen ions and free radicals, detoxified by the system to mitigate cell damage.
If the body cannot detoxify these ROS, oxidative stress may increase until apoptosis (programmed cell death) occurs. Several progressive diseases involve oxidative stress, including Alzheimer’s disease, Parkinson’s and Fragile X syndrome, as well as cancer itself.
In normal cells, low levels of ROS are necessary to allow signal transduction into healthy cells. If these cells are carcinogenic, they require high levels of ROS to allow the increase of the metabolic ratio and the ratio of division and proliferation; therefore, oxidative stress generally promotes cancer proliferation. However, CBD-induced oxidative stress can actually lead to apoptosis in certain types of cancer cells, particularly in human breast carcinoma.
Disadvantages of CBD oil
Not everything is as perfect as it sounds. CBD oil has multiple disadvantages, among the most important highlights the bioavailability, which is a pharmacokinetic concept that alludes to the fraction and speed at which the administered dose of a drug reaches its therapeutic target (channels, transporters and receptors, being these protein macromolecules), which implies reaching the tissue where it acts.
Bioavailability, in the case of CBD oil, is very low. The pharmaceutical industry has had to reinvent its product, looking for alternative ways that would allow it to create a drug with greater absorbing power for the body, and thus was born the CBD soluble in water.
Bioavailability is one of the most important characteristics of any drug, and one of the fundamental elements on which any pharmaceutical company focuses and seeks to improve. The inability of cannabinoids to dissolve in water was a major limitation in developing products for healthy consumption. Multiple companies have devoted all their resources to create a product based on water-soluble THC and CBD.
Our bodies are mainly water, the percentages can vary a little between men or women, their weight, their age, etc. but are close to 60-70%. The most important organs, such as the brain, are mainly water (up to 80%). If what we are looking for is to make the drug more effective, the most important characteristic we must achieve is to make the product hydro-soluble (soluble in water).
In the pharmaceutical industry, side effects are a crucial point in drugs. One of the most important reasons these effects appear is because of the poor bioavailability of drugs. Our body can absorb only 10% of any non-soluble product, which means you need to take 10 times the necessary dose to have an effect.
If so, what happens to the other 90% of the product? Unlike most water-soluble molecules – which freely cross the cell barrier and spread widely throughout the body almost instantaneously – These oil-based molecules or drugs have very slow transport and are stored in fat, where they can reach highly toxic levels. Because of this unwanted accumulation, they can cause disorders such as diarrhea, vomiting, nausea, fever, and many other side effects.
With all these large pharmaceutical companies seeking to innovate and be the first in the market to offer a quality product, it was only a matter of time before they reached the solution.
Water CBD vs CBD Oil
Although bioavailability is an essential factor –the most important one-, it is not the only difference between these products. Some of them are:
Taste: with no doubt, one of the most important differences is the taste of each of these products. CBD oil -especially those that are of high quality- has a terrible taste, unless they add special flavorings, which end up being harmful to our organism.
Speed: We are not referring to the simple fact it is easier to consume water than oil. When you suffer from pain, especially in uncomfortable places, you always require quick relief. We can get this with Water CBD, thanks to the speed of absorption and distribution it has in our organism.
Safety: By consuming CBD oil, we are also consuming the fatty part of the product! Water CBD is calorie-free, which means it is much healthier than CBD oil! Many of the big manufacturers of CBD oil ended up using multiple other compounds to try to improve its bioavailability, compounds that are not suitable for the body. They even lied about the product content.
Is Water CBD the perfect product?
To be honest, the short answer is no. One of the most important problems lies at its core, the base of its creation, the nanotechnology. While many researchers say it greatly increases bioavailability, very few mentions the increased toxicity it could bring with it. Researchers relate all this to “nanoceuticals”, molecules and chemicals part of the new nanotechnology, which can be harmful to the body. In fact, there is no regulation based on the use of these molecules, which is undoubtedly a risk to consumers.
You should also know most manufacturers isolated CBD, which means all those properties and benefits we get from THC – even at low concentrations – will no longer be present. Let us remember that one of the most important faculties is the synergy that exists between CBD and THC. Although the last one is thought to be a purely psychoactive agent, combined with CBD and certain terpenes -which are also present in multiple varieties of Cannabis- can contribute to improving certain pathologies, which CBD alone cannot. Of course, all this is still under study, but its future is quite promising.
Should you consume water CBD?
Many of those who tried to test the CBD as a therapeutic agent had their reservations. First, it is a direct derivative of Cannabis – so its psychotropic effects would always be something to discuss, even if they did not really exist – but also because of the way you have to consume it. Most people were unaware that smoking was unnecessary to consume the product. In fact, even with the advent of CBD oil, people were not at all pleased. While they wanted its benefits, the method of consumption may not have been the best.
It was impossible to consume the daily dose publicly since everyone would notice you were consuming Cannabis. Now the game has changed, even to the level at which the water-soluble CBD for athletes is actually in the approval phase. Research suggests that it may alleviate many of the disorders athletes frequently suffer from. Let us remember that one of the key points of CBD – in terms of its therapeutic benefits – is its analgesic and anti-inflammatory capacity, which would be ideal for an athlete after exercise.
With no doubt, Water CBD is an extremely incredible product because it allows consuming the Cannabidiol in a way we could not have imagined, where you can be sure the product will get straight to where it has to go to have a quick effect. Besides that, it is a great alternative if you tolerate neither the smell nor the taste of CBD oil! In addition, let us not forget that being water, it is still refreshing!